Table 2.
Information of hub genes related to SKCM identified by GWAS.
| Gene name | Chr | Start (bp) | End (bp) | Strand | Description |
|---|---|---|---|---|---|
| SLC45A2 | 5 | 33946602 | 33956490 | – | Solute carrier family 45 member 2 |
| OCA2 | 15 | 27871154 | 28099370 | – | OCA2 melanosomal transmembrane protein |
| TYRP1 | 9 | 12685439 | 12710285 | + | Tyrosinase related protein 1 |
| CDKN2A | 9 | 21967752 | 21995301 | – | Cyclin dependent kinase inhibitor 2A |
| SLC24A5 | 15 | 48120990 | 48142672 | + | Solute carrier family 24 member 5 |
| MC1R | 16 | 89912119 | 89920973 | + | Melanocortin 1 receptor |
| KITLG | 12 | 88492793 | 88580851 | – | KIT ligand |
| MITF | 3 | 69739464 | 69968336 | + | Melanocyte inducing transcription factor |
| TYR | 11 | 89177875 | 89295759 | + | Tyrosinase |
| TP53 | 17 | 7661779 | 7687538 | – | Tumor protein p53 |