Table 4.
Univariate analysis of lymph node metastasis and clinicopathological factors in EGC.
| Risk factor | lymph node metastasis | ||
|---|---|---|---|
| OR | 95% CI | P | |
| Sex | 0.781 | ||
| Male | Reference | ||
| Female | 0.943 | 0.624-1.425 | |
| Age | 0.683 | ||
| >60 | Reference | ||
| ≤60 | 1.091 | 0.718-1.659 | |
| Depth of invasion | 0.011 | ||
| Mucosa | Reference | ||
| Submucosa | 1.803 | 1.143-2.845 | |
| Differentiation type | <0.001 | ||
| Well differentiated | Reference | ||
| Undifferentiated | 2.138 | 1.424-3.209 | |
| Lesion location | |||
| Lower cancer | Reference | 0.240 | |
| Middle cancer | 1.028 | 0.663-1.594 | |
| Upper cancer | 1.591 | 0.906-2.794 | |
| Tumor diameter | 0.036 | ||
| <1 cm | Reference | ||
| 1~3 cm | 1.243 | 0.674-2.289 | |
| >3 cm | 1.964 | 1.064-3.625 | |
| Macroscopic type | 0.036 | ||
| Elevated type | Reference | ||
| Flat type | 1.083 | 0.552-2.126 | |
| Depressed type | 1.807 | 1.020-3.201 | |
| Morphological ulceration | 0.010 | ||
| No | Reference | ||
| Yes | 1.726 | 1.139-2.615 | |
| LVI | <0.001 | ||
| No | Reference | ||
| Yes | 3.285 | 1.751-6.161 | |
| Serum CEA | 0.305 | ||
| <5 ng/ml | Reference | ||
| ≥5 ng/ml | 1.415 | 0.729-2.749 | |
| Retrieved LN | 0.168 | ||
| <15 | Reference | ||
| ≥15 | 1.350 | 0.880-2.070 | |
LVI, lymphovascular invasion; CEA, Carcinoembryonic antigen; LNM, lymph node metastasis; LN, lymph nodes.