Table 1.

Univariate analysis of the degree of disability in MS patients.

Index	≤3 (n = 45)	>3 (n = 27)	t/z/χ2	P
EDSS score	5.16 ± 3.25	6.78 ± 2.99	−2.11a	0.038*
Age	36.29 ± 11.27	42.59 ± 11.81	−2.257a	0.027*
Male/Female	19/26	8/19	1.142b	0.285
ARR	1.00 (1.00, 1.75)	0.73 (0.44, 1.00)	−2.554c	0.011*
Number of relapses	2.00 (1.00, 3.00)	4.00 (2.00, 8.00)	−3.602c	<0.001**
Disease duration	1.00 (1.00, 4.50)	8.00 (2.00, 13.00)	−3.815c	<0.001**
BMI	22.98 ± 4.05	22.39 ± 2.75	0.737a	0.464
Drug use [n (%)]	23 (51.1)	6 (22.2)	5.855b	0.016*
TP	67.61 ± 4.35	68.27 ± 5.11	−0.586a	0.560
Alb	44.05 ± 4.22	41.49 ± 4.22	2.498a	0.015*
PAB	278 ± 63.81	257.67 ± 75.39	1.222a	0.226
TC (mmol/L)	4.32 ± 0.98	4.25 ± 1.05	0.282a	0.779
TG (mmol/L)	0.92 (0.60, 1.58)	1.25 (1.02, 1.48)	−2.123c	0.034*
HDL (mmol/L)	1.16 ± 0.28	1.15 ± 0.33	0.130a	0.897
LDL (mmol/L)	2.53 ± 0.73	2.47 ± 0.92	0.299a	0.766
Total number of lesions	1.00 (1.00, 2.00)	2.00 (1.00, 2.00)	−2.841c	0.004**
Enhanced lesions [n (%)]	19 (42.2)	13 (48.1)	0.240b	0.624

^*P < 0.05,

^** P < 0.01;

^a : the t value of the independent sample t-test;

^b : theχ²value of theχ²test;

^c: the Z value of the Mann-Whitney U test. Univariate analysis showed that the age, ARR, number of relapses, disease duration, drug use, ALB, TG and total number of lesions in groups with an EDSS score ≤ 3 were significantly different from an EDSS score> 3 (P < 0.05).