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. 2021 Oct 27;10(11):e1351. doi: 10.1002/cti2.1351

Figure 2.

Figure 2

The dynamic changes in the intratumoral clonotypes (ITCs) detected in the peripheral blood during R‐CHOP, stratified by their abundance in the intratumoral repertoire. The proportion of ITCs detected in the peripheral blood at baseline (Pre‐Rx) and after four cycles of R‐CHOP (post‐c#4) are shown for (a) all ITCs (ITC‐all), (b) the most abundant 100 ITCs (ITC‐100) and (c) the most abundant 25 ITCs (ITC‐25). Although a greater proportion of ITC‐100 and ITC‐25 were detected in peripheral blood, there was significant reduction during treatment.