Table 1. Producing Bacterial Strain and Bioactivity of Known Avi(Me)Cys-Containing Peptides (G+ = Gram-Positive, G– = Gram-Negative).

family	peptide	producing strain	notable bioactivity
lanthipeptide	mutacin-114017 (class I)	Streptococcus mutans	Neisseria gonorrhea (G−), Enterococcus faecalis (G+), Staphylococcus epidermidis (G+), Helicobacter pylori (G−)
	microbisporicins18 (class I)	Microbispora corallina	Staphylococcus aureus (G+), Streptococcus pneumoniae (G+)
	gallidermin19 (class I)	Staphylococcus gallinarum	Mariniluteicoccus flavus (G+), Staphylococcus simulans (G+)
	epidermin20 (class I)	Staphylococcus epidermidis	Mariniluteicoccus flavus (G+), Staphylococcus simulans (G+)
	clausin21 (class I)	Bacillus clausii O/C	Clostridium difficile (G+)
	BsaA237 (class I)	Staphylococcus aureus	antibacterial (G+)
	mersacidin22 (class II)	Bacillus amyloliquefaciens	Staphylococcus aureus (G+), MRSA (G+)
	lexapeptide23 (class V)	Streptomyces rochei	MRSA (G+), MRSE (G+), Micrococcus luteus (G+), Bacillus subtilis (G+)
	daspyromycin A and B38 (unknown class)	Actinokineospora diospyrosa NBRC 15665	MRSA (G+), VRE (G+)
linaridin	cypemycin39,40	Streptomyces sp. OH-4156	cytotoxic against P388 leukemia cells, antibacterial against Micrococcus luteus
	grisemycin41	Streptomyces griseus	not reported
	salinipeptins A–D42	Streptomyces sp. strain GSL-6C	group A Streptococcus pyogenes M1T1
thioamitide	thioviridamide5	Streptomyces olivoviridis	apoptosis inducer (anticancer)
	TVA-YJ-4, 5, and 643	Streptomyces sp. NRRL S-87	cytotoxic (anticancer)
	thioholgamides A and B44	Streptomyces malayseiense	antiproliferative and cytotoxic (anticancer)
	thiostreptamide S445	Streptomyces sp. NRRL S-4	anticancer (specific activity yet to be reported)
	thiosparsoamide46	Streptomyces sparsogenes
	thioalbamide47	Amycolatopsis alba
	JBIR-14048	Streptomyces avermitilis
	TVA-YJ-149	Streptomyces laurentii
lipolanthine	microvionin50	Microbacterium arborescens	MRSA (G+), Streptococcus pneumoniae (G+)
	nocavionin50	Nocardia terpenica	not reported
	goadvionins51	Streptomyces sp. TP-A0584	Staphylococcus aureus (G+), Bacillus subtilis (G+), Micrococcus luteus (G+)
lanthidin	cacaoidin52	Streptomyces cacaoi	MRSA (G+), Clostridium difficile (G+), Staphylococcus simulans (G+)