Table 1:
Table of fibre populations and sensory properties of healthy control and diabetic mice
| Healthy control mice | diabetic mice | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| strain | fiber type | n | cv (m/s) | median v. Frey (mN) | electrical threshold | heat threshold (°C) | n | cv (m/s) | median v. Frey (mN) | electrical threshold | heat threshold (°C) |
| C57BL/6 | C-MH | 14 | 0.42 ± 0.02 | 4 | 3.3 ± 1.4 | 37.9 ± 0.7 | 6 | 0.52 ± 0.06 | 5.7 | 4.6 ± 2.6 | 39.4 ± 1.3 |
| C-MHC | 3 | 6 | |||||||||
| C-MC | -- | 3 | |||||||||
| C-HTM | 4 | 0.24 ± 0.04 | 8 | 5 ± 3.2 | -- | 2 | 0.28 ± 0.06 | 5.7 | 0.09 ± 0.07 | -- | |
| C-LTM | 3 | 0.3 ± 0.01 | 2 | 0.5 ± 0.9 | -- | 3 | 0.5 ± 0.1 | 2 | 8.1 ± 6.9 | -- | |
| Cav3.2 −/− | C-MH | 6 | 0.49 ± 0.06 | 4.8 | 5.7 ± 1.7 | 37.9 ± 1 | 5 | 0.6 ± 0.2 | 2.4 | 4.2 ± 2.4 | 43.7 ± 1.2 |
| C-MHC | 3 | 2 | |||||||||
| C-MC | 1 | 3 | |||||||||
| C-HTM | 7 | 0.45 ± 0.06 | 5.7 | 10.9 ± 3.8 | -- | 7 | 0.49 ± 0.1 | 5.7 | 1.5 ± 1.1 | ||
| C-LTM | 2 | 0.5 ± 0.14 | 1 | 2 ± 0.7 | -- | 7 | 0.23 ± 0.04 | 4 | 3.3 ± 2.3 | -- | |
C-MH, mechano, heat-sensitive; C-MHC, mechano, heat, cooling-sensitive, C-MC, mechano-cold sensitive; C-LTM, low threshold mechano-sensitive; HTM, high threshold mechano-sensitive