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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: Glia. 2020 Oct 31;69(4):858–871. doi: 10.1002/glia.23932

FIGURE 1.

FIGURE 1

In vivo HIV-specific CTL-mediated killing of peptide-loaded splenocytes. (a) BALB/c and C57BL/6 mice were primed with rAd5-p24. Seven days later, in vivo cytotoxicity was determined 18 hr following intravenous injection of each mouse with syngeneic CFSE-labeled splenocytes pulsed with 1 μg/ml of the HIV-specific AI9 or YI9 peptide. (b) Representative histograms showing CFSE-labeled cells recovered from spleens of rAd5-p24 immunized hosts. Insets are the representative no peptide controls. (c) Graphical representation of % CTL activity [1 − (control group hi/lo ratio: experimental group hi/lo ratio)] × 100. Data shown are representative of three independent experiments