Table 2.
Disease clusters enriched with differential proteins of the two Syndromes
| Syndrome | Enrichment score/Rank | Disease term | #Mapped genes | Total genes | Percentage | P |
|---|---|---|---|---|---|---|
| CCQS | 3.69/1 | Myocardial infarct | 5 | 121 | 20.83% | 2.51E−05 |
| Coronary Artery Disease| | 4 | 52 | 16.67% | 5.63E−05 | ||
| 3.39/2 |
Coronary Disease|Coronary heart disease| Inflammation|Insulin Resistance |
5 | 59 | 20.83% | 1.42E−06 | |
| Atherosclerosis, coronary | 5 | 155 | 20.83% | 6.61E−05 | ||
| Cardiovascular disease | 4 | 59 | 16.67% | 8.23E−05 | ||
| Metabolic syndrome | 4 | 165 | 16.67% | 0.00168 | ||
| Obesity | 5 | 369 | 20.83% | 0.00177 | ||
| Cardiovascular Diseases | 4 | 189 | 16.67% | 0.00248 | ||
| Diabetes, type 2 | 5 | 439 | 20.83% | 0.00334 | ||
| QSBS | 5.26/1 | Myocardial ischemia | 5 | 18 | 21.74% | 7.85E−09 |
| Carotid atherosclerosis | 5 | 21 | 21.74% | 1.53E−08 | ||
| Atherosclerosis, coronary | 6 | 155 | 26.09% | 1.73E−06 | ||
| Recurrence|Venous Thromboembolism | 4 | 58 | 17.39% | 6.60E−05 | ||
| Brain Ischemia|Hypertension|Osteoporosis|Stroke | 4 | 64 | 17.39% | 8.87E−05 | ||
| Cardiovascular Diseases | 4 | 67 | 17.39% | 1.02E−04 | ||
| Alzheimer's disease | 5 | 950 | 21.74% | 0.03828 |