Table 1.
α-Glucosidase and α-amylase inhibitory potentials of Notholirion thomsonianum
| Samples | Conc (μg/mL) |
Alpha glucosidase | Alpha amylase | ||
|---|---|---|---|---|---|
| Percent Inhibition (mean ± SEM) |
IC50 (μg/mL) |
Percent Inhibition (mean ± SEM) |
IC50 (μg/mL) |
||
| Nt.Cr |
1000 500 250 125 62.5 |
64.78 ± 0.92*** 54.11 ± 0.07*** 51.55 ± 0.41*** 47.55 ± 0.67*** 40.00 ± 0.57*** |
185 |
62.41 ± 0.24** 57.65 ± 0.01*** 54.62 ± 0.63** 45.32 ± 0.41*** 41.10 ± 0.48*** |
180 |
| Nt.Hex |
1000 500 250 125 62.5 |
57.44 ± 0.60*** 51.45 ± 0.57*** 44.84 ± 0.39*** 39.13 ± 0.92*** 32.00 ± 1.00*** |
435 |
60.52 ± 0.52** 57.52 ± 0.52*** 50.24 ± 0.27** 46.52 ± 0.51*** 38.22 ± 0.82*** |
240 |
| Nt.Chf |
1000 500 250 125 62.5 |
59.69 ± 1.21*** 53.88 ± 1.04*** 47.28 ± 1.15*** 42.31 ± 0.48*** 35.00 ± 0.00*** |
394 |
56.53 ± 1.01*** 51.23 ± 0.86*** 43.52 ± 1.03*** 39.12 ± 0.93*** 36.53 ± 0.52*** |
450 |
| Nt.EtAc |
1000 500 250 125 62.5 |
68.57 ± 1.26*** 61.89 ± 1.70*** 57.77 ± 1.01*** 53.61 ± 2.31*** 45.33 ± 0.66*** |
67 |
71.30 ± 0.83ns 64.42 ± 1.20 ns 60.52 ± 1.54ns 55.63 ± 1.65ns 48.35 ± 1.08 ns |
70 |
| Nt.Aq |
1000 500 250 125 62.5 |
55.77 ± 0.95*** 48.55 ± 1.75*** 39.35 ± 0.21*** 33.75 ± 0.44*** 28.00 ± 0.00*** |
614 |
47.53 ± 0.24*** 43.74 ± 1.32*** 37.52 ± 1.54*** 29.32 ± 0.63*** 26.53 ± 0.27*** |
950 |
| Acarbose |
1000 500 250 125 62.5 |
76.87 ± 0.06 73.94 ± 1.92 67.49 ± 0.22 61.53 ± 0.89 55.50 ± 1.00 |
6.84 |
78.63 ± 0.54 71.65 ± 0.71 68.95 ± 1.20 64.52 ± 0.21 57.63 ± 0.59 |
13 |