Table 2.
Pooled estimates of the regression coefficients ORs and the 95% CrIs for each one of the parameters in the model (centralized to the mean), using Rubin’s rules. The estimated σ (standard deviation of the impact of the variables on multiple observations for the same individuals) is 0.01. The estimated correlation ρ between the effects of the variables is 0.49. The pooled optimism-corrected AUC is 0.65 and the pooled optimism-corrected calibration slope is 0.91. Disease duration was transformed to log(disease duration+10), and months since last relapse was transformed to log(months since last relapse+10)
| Parameters | OR | 95% CrI | |
|---|---|---|---|
| Age | -0.035 | 0.97 | (0.95, 0.98) |
| Disease duration | 0.337 | 1.40 | (0.90, 2.18) |
| EDSS | 0.122 | 1.13 | (1.02, 1.25) |
| Number of gadolinium-enhanced lesions (> 0 vs 0) | − 0.034 | 0.97 | (0.69, 1.36) |
| Number of previous relapses (1 vs 0) | − 0.070 | 0.93 | (0.69, 1.26) |
| Number of previous relapses (2 or more vs 0) | 0.133 | 1.14 | (0.81, 1.61) |
| Months since last relapse | − 0.478 | 0.62 | (0.49, 0.78) |
| Treatment naïve (yes vs no) | 0.086 | 1.09 | (0.80, 1.49) |
| Gender (female vs male) | 0.254 | 1.29 | (0.97, 1.72) |
| On treatment (yes vs no) | − 0.221 | 0.80 | (0.50, 1.27) |