Heat map of the antibiotic-sensitivity profile of Brasília
K. pneumoniae
clinical isolates as assessed by Vitek 2. Resistance (red) or sensitivity (blue) against a particular antibiotic is defined using the European Committee on Antimicrobial Susceptibility Testing (EUCAST) clinical breakpoint at the time of isolation. Missing antibiotic information is shown in white. Antibiotics tested included antibiotics from the following classes (indicated by Roman numerals). (I) Penicillins, which included amp_sulbac (ampicillin/sulbactam), ampicillin, aztreonam, pip_tazo (piperacillin/tazobactam) and piperacillin. (II) Carbapenems, which included ertapenem, imipenem and meropenem. (III) Second-generation cephalosporins, which included cefalotin, cefuroxime and cefotetan. (IV) Third-generation cephalosporins, which included cefotaxime, ceftazidime and ceftriaxone. (V) Fourth-generation cephalosporins, which included cefepime. (VI) Quinolones, which included levofloxacin and ciprofloxacin. (VII) Aminoglycosides, which included amikacin, gentamicin, tobramycin. The complete profile with MIC values is available in Table S7.