Table 1.
Group of interest | Patient control group | Healthy control group | |
---|---|---|---|
Step 1 | 134 ovarian Germ Cell Tumor or Sex Cord Stromal tumor survivors | 67 ovarian Germ Cell Tumor or Sex Cord Stromal tumor survivors | 67 healthy women |
Step 2 | 90 ovarian Germ Cell Tumor or Sex Cord Stromal tumors survivors | 45 ovarian Germ Cell Tumor or Sex Cord Stromal tumor survivors | Not applicablea |
Inclusion criteria | ≥ 18 years old | ≥ 18 years old | ≥ 18 years old |
Age-matched to group of interest (± 2 years) | Age-matched to group of interest (± 2 years) | ||
Patient treated with surgery and BEP chemotherapy (≥ 1 cycle) | Patient treated with surgery alone (with or without fertility sparing). | ||
Patient in remission ≥2 years after initial treatment | Patient in remission ≥2 years after initial treatment | ||
Recurrence authorized if remission more than 2 years after end of initial treatment | Recurrence authorized if remission more than 2 years after the end of initial treatment | ||
Patient with no other cancers (except basal cell skin carcinoma, breast cancer and cervical cancer) | Patient with no other cancers (except basal cell skin carcinoma, breast cancer and cervical cancer) | Women without cancer or serious chronic diseases | |
Patient having signed consent to participate | Patient having signed consent to participate | Healthy women accepted to complete online self-reported questionnaires | |
Exclusion criteria | Pregnant or breastfeeding woman | ||
Psychiatric disorders | |||
Major subject to legal protection or unable to express consent |
BEP Bleomycin, Etoposide and Cisplatinum
a: Healthy control group participated only in step 1 of study (self-reported questionnaire)