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. 2021 Oct 26;21:1147. doi: 10.1186/s12885-021-08864-8

Table 1.

Study inclusion and exclusion criteria

Group of interest Patient control group Healthy control group
Step 1 134 ovarian Germ Cell Tumor or Sex Cord Stromal tumor survivors 67 ovarian Germ Cell Tumor or Sex Cord Stromal tumor survivors 67 healthy women
Step 2 90 ovarian Germ Cell Tumor or Sex Cord Stromal tumors survivors 45 ovarian Germ Cell Tumor or Sex Cord Stromal tumor survivors Not applicablea
Inclusion criteria ≥ 18 years old ≥ 18 years old ≥ 18 years old
Age-matched to group of interest (± 2 years) Age-matched to group of interest (± 2 years)
Patient treated with surgery and BEP chemotherapy (≥ 1 cycle) Patient treated with surgery alone (with or without fertility sparing).
Patient in remission ≥2 years after initial treatment Patient in remission ≥2 years after initial treatment
Recurrence authorized if remission more than 2 years after end of initial treatment Recurrence authorized if remission more than 2 years after the end of initial treatment
Patient with no other cancers (except basal cell skin carcinoma, breast cancer and cervical cancer) Patient with no other cancers (except basal cell skin carcinoma, breast cancer and cervical cancer) Women without cancer or serious chronic diseases
Patient having signed consent to participate Patient having signed consent to participate Healthy women accepted to complete online self-reported questionnaires
Exclusion criteria Pregnant or breastfeeding woman
Psychiatric disorders
Major subject to legal protection or unable to express consent

BEP Bleomycin, Etoposide and Cisplatinum

a: Healthy control group participated only in step 1 of study (self-reported questionnaire)