Table 2.
Self-reported questionnaires used in study
| Questionnaires | Scoring | Definition of scoring |
|---|---|---|
| Chronic fatigue | ||
|
Fatigue MFI-20 items |
5 dimensions of fatigue: -General fatigue -Physical fatigue -Reduced motivation -Reduced activity -Mental fatigue |
High score indicates high level of fatigue |
| Global quality of lifea | ||
|
Global QoL FACT-G |
4 dimensions: 0–4 Likert scale - PWB: 7 items, score range: 0–28 - SWB: 7 items, score range: 0–28 - EWB: 6 items, score range: 0–24 - FWB: 7 items, score range: 0–28 Total score: 0–108 |
A lower score indicates a lower QoL dimension |
| Additional concerns subscalea | ||
|
EOC specific concerns FACT-O |
0–4 Likert scale Score: 0–44 |
A lower score indicates a severe symptom |
| A lower score indicates a high level of fatigue | ||
|
Neurotoxicity FACT/GOG-Ntx |
0–4 Likert scale Score range: 0–44 |
A lower score indicates a worse neuropathy Score < 33 ≈ Severe neuropathy |
| TOI = PWB + FWB + concerns subscalea | ||
| FACT-F/TOI | Score range: 0–108 | A lower score indicates a severe symptom |
| FACT/GOG-Ntx/TOI | Score range: 0–100 | |
| FACT-Cog | Score range: 0–100 | |
| FACT-O/ TOI | Score range: 0–100 | |
| Other dimensions of QoL | ||
|
Anxiety & Depression HADS |
Anxiety: 7 items, score range: 0–21 Depression:7 items, score range: 0–21 |
Score ≥ 8 ≈ elevated anxiety, Score ≥ 8 ≈ elevated depression, |
|
Sleep disturbance ISI |
0–5 Likert scale Score range: 0–28 |
A higher total score indicates more severe sleep difficulties Score 22–28 ≈ Severe clinical insomnia |
|
Physical activity IPAQ |
3 levels of physical activity (categorical score)b | High/ moderate/low level of physical activity |
| Conditions of life | ||
| Living conditions questionnaire [25] | Daily life of participants (family, social and professional situation) | NA |
| Assessment and comparison of the costs of sequelae in the 2 groups of patients | ||
| Euroqol (EQ-5D 5 L) questionnaire | Generic measure for clinical and economic assessment | Utility score associated with state of health. |
a: Clinically significant difference: variation of 5%, b: Responses are categorized into three levels of physical activity: low (<moderate); moderate (3 or more days/week of vigorous activity of at least 20 min/day or 5 or more days/week of moderate activity, or 30 min/day walking) and high (vigorous activity on at least 3 days or 7 days/week of any combination of walking, moderate or vigorous intensity activities). MFI Multidimensional Fatigue Inventory -QoL Quality of Life, FACT-G General Functional Assessment of Cancer Therapy, PWB Physical Well-Being, SWB Social/family Well-Being, EWB Emotional Well-Being, FWB Functional Well-Being, EOC Epithelial Ovarian Cancer, FACT-O Functional Assessment of Chronic Therapy- Ovarian subscale, FACT-F Functional Assessment of Chronic Therapy-Fatigue subscale, FACT/GOG-Ntx Functional Assessment of Cancer Therapy/ Gynecologic Oncology Group–Neurotoxicity subscale, FACT-Cog Functional Assessment of Cancer Therapy-Cognitive, TOI Trial Outcome Index, ISI Insomnia Severity Index, HADS Hospital Anxiety and Depression Scale, IPAQ International Physical Activity Questionnaire, NA Not Adapted