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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Am J Surg Pathol. 2021 Jan;45(1):25–34. doi: 10.1097/PAS.0000000000001602

Figure 2:

Figure 2:

Case 12: Biopsy of distal esophagus showing a mixed adenoneuroendocrine carcinoma (A, H&E) with diffuse synaptophysin positivity in the neuroendocrine component (B). Post-treatment resection specimen shows residual viable neuroendocrine carcinoma component (C) with corresponding low Ki67 (D).