S. enterica and E. coli enhance poliovirus's infectivity, a closely related enteric virus. We incubated 105 PFU of poliovirus with DMEM or 107 of E. coli or S. enterica at 37°C for 6 h, followed by a plaque assay on HeLa cells. Data represent 3 independent experiments (n = 6); bars represent mean ± SEM, *, P < 0.05; **, P < 0.01; one-way ANOVA.