FIG 6.

Sensitivity of different Spike proteins to convalescent serum neutralization. Indicated VSV-Luc pseudoviruses were incubated with serially diluted sera (1:10- to 1:7,290-fold) from control or convalescent COVID-19 patients (CCS) for 30 min before addition to HeLa-ACE2 cells. Luciferase activity was determined 24 h later. All values were normalized to the luciferase signal from cells transduced with the same pseudovirus without serum. Means and standard deviations from 3 technical replicates of single vector stocks are shown.