TABLE 3.

Comparisons between the different measurements of TBI severity outcome. (A) Comparison of the correlation between the different parameters of TBI severity outcome 48 h after TBI by either histological and MRI-determined techniques. (B) Determination of the outcomes with the highest correlation values.

Deferent TBI outcomes		Histological			MRI
		BBB breakdown	Lesion volume	Brain edema	BBB breakdown	Lesion volume	Brain edema
Histological	BBB breakdown
	Lesion volume	rp = 0.540 p < 0.001
	Brain edema	rp = 0.687 p < 0.001	rp = 0.657 p < 0.001
MRI	BBB breakdown	rp = 0.503 p < 0.001	rp = 0.432 p < 0.001	rp = 0.625 p < 0.001
	Lesion volume	rp = 0.430 p < 0.001	rp = 0.361 p < 0.01	rp = 0.481 p < 0.001	rp = 0.577 p < 0.001
	Brain edema	rp = 0.537 p < 0.001	rp = 0.478 p < 0.001	rp = 0.757 p < 0.001	rp = 0.539 p < 0.001	rp = 0.337 p < 0.01
NSS		rs = 0.860 p < 0.001	rs = 0.674 p < 0.001	rs = 0.785 p < 0.001	rs = 0.776 p < 0.001	rs = 0.656 p < 0.001	rs = 0.706 p < 0.001
A
			High	Moderate	Low	Total correlation index
NSS			4	2	0	4.457
MRI		BBB breakdown	1	4	1	3.452	9.648
		Lesion volume	0	2	4	2.842
		Brain edema	2	2	2	3.354
Histological		BBB breakdown	1	4	1	3.557	10.691
		Lesion volume	0	3	3	3.142
		Brain edema	2	3	1	3.992
B