Comparative genomic analysis of the virulence and resistance plasmids. (a) Alignment analysis of virulence plasmid sequences among pVir-C1672, pVir-C2051, and previously reported virulence plasmids, including pLVPK (accession no. AY378100) and pTHC11-1 (accession no. AP019549). (b) The region containing resistance genes in pRes-C1672 and pRes-C2051. (c) Comparison of pRes-C1672 and pRes-C2051 resistance plasmids from this study with 10 complete resistance plasmids bearing blaIMP that originated from K. pneumoniae strains and whose sequences were downloaded from the RefSeq database, as well as pTHC11-2 (accession no. AP019550). The maximum-likelihood phylogenetic tree was built by RaxML from an alignment generated by Roary and filtered to remove recombination using ClonalFrameML. The Interactive Tree Of Life (https://itol.embl.de) was used for visualization. The bootstraps are shown as blue circles on the branches. (d) Alignment analysis of resistance plasmid sequences among pRes-C1672, pRes-C2051, and previously reported resistance plasmids pTHC11-2 (accession no. AP019550) and GCF_008632115.1 (accession no. CM018324).