TABLE 1.
Comparison of baseline characteristics for the mRDT + ASP and CONV + ASP groupsa
| Characteristicb | mRDT + ASP group (n = 164) | CONV + ASP group (n = 214) | P value |
|---|---|---|---|
| Age (yrs) (mean ± SD) | 59.5 ± 15.7 | 62.9 ± 16.9 | 0.054 |
| Female sex | 71 (43.3) | 95 (44.4) | 0.100 |
| Race/ethnicity | |||
| Black | 79 (48.2) | 58 (27) | 0.189 |
| Non-Hispanic white | 76 (46.3) | 143 (66.8) | 0.096 |
| Hispanic | 9 (5.5) | 9 (4.2) | 0.254 |
| Beta-lactam allergy | 33 (20.1) | 35 (16.4) | 0.301 |
| NH/LTC residence | 36 (22) | 41 (19.2) | 0.562 |
| Immunosuppressive medication | 13 (7.9) | 13 (6.1) | 0.275 |
| Surgical procedure within previous 30 days | 34 (20.7) | 41 (19.2) | 0.103 |
| Gram-negative infection within 6 months | 79 (48.2) | 87 (40.7) | 0.139 |
| History of infection due to ESBL-producing Enterobacterales | 54 (32.9) | 61 (28.5) | 0.759 |
| History of infection due to carbapenemase-producing Enterobacterales | 6 (3.7) | 2 (0.9) | 0.084 |
| Charlson comorbidity index (mean ± SD) | 6.1 ± 3.4 | 5.5 ± 2.9 | 0.275 |
| Pitt bacteremia score (mean ± SD) | 3.1 ± 2.4 | 3.4 ± 2.7 | 0.439 |
| Hospital-acquired infection | 84 (51.2) | 94 (43.9) | 0.233 |
| Index culture results | |||
| ESBL-producing Enterobacterales | 150 (91.5) | 203 (94.9) | 0.807 |
| E. coli | 86 (57.3) | 129 (63.5) | 0.237 |
| K. pneumoniae | 64 (42.7) | 74 (36.5) | |
| Carbapenemase-producing Enterobacterales | 14 (8.5) | 11 (5.1) | 0.219 |
| E. coli | 0 (0) | 1 (9) | 0.441 |
| K. pneumoniae | 14 (100) | 10 (91) | |
| ID consult | 57 (34.8) | 176 (82.2) | <0.001 |
| Sources | |||
| Endovascular | 13 (7.9) | 22 (10.3) | |
| Intra-abdominal | 20 (12.2) | 30 (14.1) | |
| Genitourinary | 85 (51.8) | 98 (45.8) | |
| Respiratory | 12 (7.3) | 20 (9.3) | |
| SSTI | 15 (9.1) | 19 (8.9) | |
| Other/unknown | 19 (11.6) | 25 (11.7) |
a
Data presented as n (%) unless specified otherwise.
b
NH/LTC, nursing home/long-term care; ESBL, extended-spectrum beta-lactamase; ID, infectious diseases; SSTI, skin and soft tissue infection.