TABLE 4.
Logistical attributes of SARS-CoV-2 serological assaysa
| Assay | Accuracy | Technical requirements | Assay time | Price | Detection method |
|---|---|---|---|---|---|
| ELISA | |||||
| RBD | ++ | + | + | $ | Enzymatic reaction |
| N | + | + | + | $ | Enzymatic reaction |
| Spike | ++ | + | + | $ | Enzymatic reaction |
| Neutralization | |||||
| Authentic virus | +++ | +++ | +++ | $$$ | Infectious unit |
| GFP pseudotype | ++ | ++ | ++ | $ | Infectious unit |
| Luci pseudotype | +++ | ++ | ++ | $$ | Enzymatic reaction |
| SEAP pseudotype | +++ | ++ | ++ | $ | Enzymatic reaction |
a
The number of symbols (+ or $) is a relative estimate of the column variable. “Price” indicates the price of running the assay given access to all the technical requirements for the assay.