Designed peptides inhibit M^pro in a dose-dependent manner. The assay conditions were 0.15 μM M^pro, 2 μM s01 in 20 mM HEPES, pH 7.5, and 50 mM NaCl.

Peptide	IC50/μM	Hill slope
p12	5.36 ± 2.17	1.25 ± 0.06
p13	3.11 ± 1.80	0.94 ± 0.09
p15	5.31 ± 1.08	1.17 ± 0.16
p16	3.76 ± 0.51	1.19 ± 0.16