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. 2020 Jun 25;69(4):701–710. doi: 10.33549/physiolres.934314

Fig. 4.

Fig. 4

Blocking Wnt/β-catenin signaling suppressed VCR-induced cytokine release. (A): ELISA showed that the protein levels of TNF-α and MCP-1 were increased at day 11 after VCR treatment (*P<0.05, versus Control group; one-way ANOVA with Bonferroni test; n=4). (B): TNF-α and MCP-1 protein levels declined after IWR administration at 18 days (*P<0.05 versus Vehicle group; one-way ANOVA with Bonferroni test; n=4). TNF-α, tumor necrosis factor-α; MCP-1, monocyte chemoattractant protein-1; IWR, the inhibitors of Wnt response.