Table 2.

Comparison of the effects of extracorporeal blood flow on hemodynamic parameters and electrical impedance of lungs in healthy circulation and heart failure conditions.

	l/min	EBF 1 Healthy	EBF 2 Healthy	EBF 3 Healthy	EBF 4 Healthy	P value Healthy
MAP	mmHg	75 ± 5	84 ± 5	*87 ± 6	**92 ± 6	< 0.01
Carotid flow	ml/min	395 ± 26	425 ± 30	*456 ± 31	435 ± 38	< 0.05
MPAP	mmHg	29 ± 4	27 ± 4	*24 ± 3	**23 ± 3	< 0.001
PCWP	mmHg	5.4 ± 0.9	5.4 ± 0.9	5.1 ± 0.5	4.4 ± 0.6	< 0.05
CVP	mmHg	4.4 ± 0.5	3.9 ± 0.5	3.3 ± 0.6	*2.6 ± 0.7	< 0.01
SvO 2	%	76 ± 3	80 ± 3	*82 ± 2	*83 ± 3	< 0.01
rSO 2 head	%	72 ± 2	73 ± 2	*76 ± 2	**76 ± 1	< 0.01
rSO 2 limb	%	69 ± 2	69 ± 2	69 ± 2	70 ± 2	ns
EIT		1.000	0.999 ± 0.006	1.006 ± 0.007	1.006 ± 0.009	ns
	l/min	EBF 1 Heart failure	EBF 2 Heart failure	EBF 3 Heart failure	EBF 4 Heart failure	P value Heart failure
MAP	mmHg	52 ± 5	53 ± 5	60 ± 4	**74 ± 6	< 0.01
Carotid flow	ml/min	258 ± 28	310 ± 43	319 ± 23	**410 ± 34	< 0.01
MPAP	mmHg	32 ± 4	29 ± 5	25 ± 3	25 ± 3	ns
PCWP	mmHg	8.3 ± 1.9	8.8 ± 2.0	10.5 ± 2.1	*10.3 ± 1.8	< 0.001
CVP	mmHg	7.5 ± 0.5	6.5 ± 0.5	6.0 ± 0.5	*5.1 ± 0.4	< 0.01
SvO 2	%	56 ± 6	67 ± 4	*74 ± 3	****84 ± 4	< 0.0001
rSO 2 head	%	52 ± 4	54 ± 5	61 ± 3	**66 ± 3	< 0.01
rSO 2 limb	%	58 ± 3	61 ± 2	62 ± 3	**65 ± 3	< 0.01
EIT		1.000	0.986 ± 0.003	**0.9785 ± 0.005	***0.9744 ± 0.006	< 0.001

Values expressed as mean ± SEM. Values significantly different to 1 l/min (EBF 1) are marked with ^* for P<0.05, ^** for P<0.01, ^*** for P<0.001, ^**** for P<0.0001. The P values reflect the whole EBF trend statistics. CVP – central venous pressure, EBF – extracorporeal blood flow, EIT – electrical impedance normalized to EBF 1, MAP – mean arterial pressure, MPAP – mean pulmonary artery pressure, PCWP – pulmonary capillary wedge pressure, ns – non-significant, rSO₂ – regional tissue oxygenation, SvO₂ – mixed venous oxygen saturation.