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. 2021 Aug 5;30(11):3307–3318. doi: 10.1007/s00586-021-06938-6

Table 5.

Factors predicting walking ability 6 weeks, 6 months and 12 months following surgery – multivariate analysis

Pre-operative factors 6 week following surgery 6 months following surgery 12 months following surgery
OR 95% CI of the OR P-value OR 95% CI of the OR P-value OR 95% CI of the OR P-value
Age categories
 < 60 Ref Ref Ref
 60–64.5 1.17 (1.03, 1.32) 0.012 1.08 (1.01, 1.24) 0.011 1.07 (1.01, 1.24) 0.021
 65–69.5 1.24 (1.07, 1.45) 0.004 0.95 (0.82, 0.99) 0.024 1.17 (1.01, 1.19) 0.042
 70–74.5 1.16 (0.97, 1.39) 0.095 0.88 (0.77, 1.39) 0.095 0.99 (0.76, 1.30) 0.986
  ≥ 75 1.62 (1.28, 2.04)  < 0.001 1.34 (1.11, 1.60) 0.007 1.54 (1.07, 2.18) 0.024
Gender
 Female Ref Ref Ref
 Male 0.98 (0.89, 1.08) 0.733 0.97 (0.88, 1.07) 0.580 0.99 (0.88, 1.11) 0.947
BMI Categories (kg/m2)
  < 20 Ref Ref Ref
 20–24.9 0.91 (0.64, 1.31) 0.646 0.86 (0.60, 1.24) 0.442 1.06 (0.93, 1.55) 0.728
 25–29.9 1.05 (0.74, 1.48) 0.770 0.94 (0.66, 1.33) 0.741 1.07 (0.75, 1.54) 0.685
 30–34.9 1.19 (0.84, 1.71) 0.322 1.08 (0.75, 1.55) 0.656 1.25 (0.87, 1.82) 0.221
 35–39.9 1.56 (1.05, 2.32) 0.027 1.24 (1.05, 1.87) 0.015 1.52 (1.00, 2.30) 0.048
  ≥ 40 1.39 (0.85, 2.29) 0.186 1.17 (1.02, 1.96) 0.005 1.34 (1.21, 5.23) 0.015
Maximum walking distance (meters) 0.99 (0.99, 1.00) 0.062 1.00 (1.02, 1.15) 0.021 1.10 (1.05, 1.25) 0.027
Time stood (minutes) 1.00 (0.98, 1.02) 0.711 1.01 (0.99, 1.02) 0.144 1.00 (0.98, 1.02) 0.501
Neurological deficit
 No Ref Ref Ref
 Yes 1.05 (0.95, 1.15) 0.313 1.00 (0.92, 1.08) 0.958 0.96 (0.86, 1.07) 0.475
Presence of comorbidity
 No Ref Ref Ref
 Yes − 0.07 (− 0.09, − 0.05) 0.242 1.33 (0.98, 1.47) 0.564 1.37 (0.98, 1.67) 0.089
Work status
 No Ref Ref Ref
 Yes 1.09 (0.81, 1.45) 0.486 1.21 (0.98, 1.47) 0.064 1.26 (0.97, 1.65) 0.072
Education
 Up to & including secondary school Ref Ref Ref
 Higher education 0.79 (0.73, 0.86)  < 0.001 0.74 (0.67, 0.81)  < 0.001 0.90 (0.80, 0.96) 0.005
Use of analgesia
 No Ref Ref Ref
 Yes 0.97 (0.71, 1.34) 0.856 0.97 (0.71, 1.34) 0.856 0.79 (0.54, 1.15) 0.190
Surgery type
 No discectomy Ref Ref Ref
 Discectomy 1.07 (0.97, 1.18) 0.156 1.25 (1.11, 1.39)  < 0.001 1.14 (1.03, 1.28) 0.013
Durations of symptoms (years) 1.00 (0.99, 1.01) 0.082 1.00 (0.99, 1.01) 0.378 1.00 (0.99, 1.01) 0.233
Zung depression score 1.01 (0.99, 1.03) 0.171 1.00 (0.98, 1.01) 0.930 1.00 (0.97, 1.03) 0.512
Fear avoidance (work) (baseline) 0.99 (0.98, 1.01) 0.748 0.99 (0.97, 1.01) 0.412 0.99 (0.97, 1.03) 0.512
Fear avoidance (pain) (baseline) 0.99 (0.97, 1.02) 0.796 1.00 (0.99, 1.01) 0.136 1.00 (0.97, 1.01) 0.776
Back pain (NRS) 1.01 (0.98, 1.03) 0.335 1.03 (0.95, 1.12) 0.156 1.00 (0.98, 1.02) 0.868
Leg pain (NRS) 0.96 (0.93, 0.99) 0.031 1.01 (1.00, 1.04) 0.007 1.10 (1.01, 1.21) 0.046
Quality of life (EQ-5D-5L Health VAS) 1.00 (0.99, 1.00) 0.662 1.00 (0.99, 1.00) 0.271 1.00 (0.99, 1.00) 0.145
Quality of life (EQ-5D-5L) 0.70 (0.53, 0.93) 0.016 0.72 (0.53, 0.98) 0.039 0.72 (0.56, 0.89) 0.037
Disability (ODI) 1.01 (1.01, 1.02)  < 0.001 1.01 (1.01, 1.02)  < 0.001 1.01 (1.01, 1.02)  < 0.001

Abbreviations: BMI: body mass index; CI: confidence interval; VAS: visual analogue scale; ODI: Oswestry Disability Index; NRS: numerical rating scale

Bold values represent p < 0.05