TABLE 3.
Assessment of LCx assay results after analysis for resolution of discrepant results (culture result plus clinical diagnosis)
| Specimen (no.) | No. of specimens MTBC positive by culture
|
No. of specimens MTBC negative by culture
|
Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | ||
|---|---|---|---|---|---|---|---|---|
| LCx assay positive | LCx assay negative | LCx positive | LCx assay negative | |||||
| All (2,347) | 115 | 50 | 1 | 2,139 | 69.7 | 99.9 | 99.1 | 97.7 |
| Respiratory (2,083) | 92 | 39 | 1 | 1,915 | 70.2 | 99.9 | 98.9 | 98.0 |
| Smear positive (139) | 65 | 1 | 0 | 60 | 98.5 | 100 | 100 | 98.4 |
| Smear negative (1,944) | 27 | 38 | 1 | 1,855 | 41.5 | 99.9 | 96.4 | 98.0 |
| Nonrespiratory (264) | 23 | 11 | 0 | 224 | 67.6 | 100 | 100 | 95.3 |