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. 2021 Oct 27;16(10):e0259096. doi: 10.1371/journal.pone.0259096

Table 1. Clinico-histopathological features among women seeking cervical cancer care at Kilimanjaro Christian Medical Centre (n = 145).

Characteristics N = 145
n (%)
Age (years) 52.1 ± 12.9
Histopathological subtype
 Benign cervical lesion
  Cervicitis 15 (10.3)
  Endocervical polyps 15 (10.3)
  Others 3 (2.1)
  Sub-total 33 (22.7)
 Precancerous cervical lesion
  CIN-1 7 (4.8)
  CIN-2 1 (0.7)
  CIN-3 3 (2.1)
  Sub-total 11 (7.6)
 Cancerous cervical lesion
  Squamous cell carcinoma 83 (57.2)
  Adenocarcinoma 6 (4.1)
  Others 6 (4.1)
  Sub-total 95 (65.4)
 Non-definitive diagnosis 6 (4.1)
  Total 145 (100)
Clinical symptoms
 PV bleeding 62 (42.7)
 Vaginal discharge 42 (29.0)
 Lower abdominal pain 34 (23.4)
 Others 7 (4.8)
Biomarkers expression
 p16
  Low 42 (29.0)
  High 103 (71.0)
 TOP2A
  Low 55 (37.9)
  Moderate 29 (20.0)
  High 61 (42.1)

mean ± standard deviation

CIN cervical intraepithelial lesion

LSIL low-grade squamous intraepithelial lesion

HSIL high-grade squamous intraepithelial lesion