Table 5. Multivariate regression analysis and the strength of association between expression levels of p16 and TOP2A in differentiating cancerous cervical lesions from benign and precancerous cervical lesions among women seeking cervical cancer care at Kilimanjaro Christian Medical Centre (n = 139).
| Variable a | Factor | Overall model significance p<0.001 | |||
|---|---|---|---|---|---|
| AOR | 95% CI for AOR | p-value | |||
| p16 | Low | 1 | |||
| High | 1.142 | 1.059 | 1.232 | <0.001 | |
| TOP2A | Low | 1 | |||
| High | 1.046 | 1.008 | 1.085 | 0.015 | |
| p16 and TOP2A | Low | 1 | |||
| High | 0.989 | 0.946 | 1.034 | 0.638 | |
CI confidence intervals
AOR age-adjusted odds ratio
a benign and precancerous cervical lesions were altogether used as a reference group