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. 2021 Sep 9;81(15):1781–1786. doi: 10.1007/s40265-021-01594-y
Small molecule inhibitor of the ileal bile acid transporter being developed by Albireo Pharma, Inc. for the treatment of various cholestatic diseases, including PFIC.
Received its first approval on 16 July 2021 in the EU.
Approved for the treatment of PFIC in patients aged ≥ 6 months in the EU and for treatment of pruritus in patients aged ≥ 3 months with PFIC in the USA.