Table 3.
Results of minimum number of individuals in reference panel, sample size and number of SNPs for accurate and stable estimates of genetic correlation and heritability in the test of various population pairs
| Population Pairs | Estimates | Values | L | N | M |
|---|---|---|---|---|---|
| EUR VS EAS | Genetic correlation | 0.1 | – | 10,000 | 102,725 |
| 0.5 | 200 | 10,000 | 123,270 | ||
| 0.9 | – | 10,000 | 143,815 | ||
| Heritability | 0.1 | – | 7,000 | 20,543 | |
| 0.5 | 500/750 | 11,000 | 41,089 | ||
| 0.9 | – | 15,000 | 123,270 | ||
| EUR VS YRI | Genetic correlation | 0.1 | – | 16,000 | 132,411 |
| 0.5 | 200 | 14,000 | 154,479 | ||
| 0.9 | – | 16,000 | 154,479 | ||
| Heritability | 0.1 | – | 7,000 | 22,067 | |
| 0.5 | 400/700 | 10,000 | 66,205 | ||
| 0.9 | – | 15,000 | 88,273 | ||
| EAS VS YRI | Genetic correlation | 0.1 | – | 10,000 | 112,034 |
| 0.5 | 300 | 10,000 | 149,379 | ||
| 0.9 | – | 9,000 | 168,052 | ||
| Heritability | 0.1 | – | 5,000 | 18,671 | |
| 0.5 | 700/700 | 9,000 | 74,689 | ||
| 0.9 | – | 13,000 | 93,362 |