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. 2021 Oct 26;15(5):051302. doi: 10.1063/5.0057733

TABLE I.

Comparison and characteristics of drop-based microfluidic technologies.

Applied technique Device material Large-scale production Advantages Disadvantages Reference
Micro-capillary assembly Glass Poor
  • Good solvent resistance

  • Precision flow control

  • Complex fabrication process

  • Limited device geometry

20 and 22
Photo/soft-lithography Polydimethylsiloxane (PDMS) Good
  • Good flexibility

  • High reproducibility

  • Poor solvent resistance

  • Difficult wettability control

41 and 42
3D printing PEG diacrylate methacrylate photoresist Excellent
  • Rapid prototyping

  • Microfluidic kit automation

  • Surface roughness

  • Low resolution channel

46 and 47