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. 2021 Oct 20;2021:5599408. doi: 10.1155/2021/5599408

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Copyright © 2021 Haiqin Jiang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Relative levels of IFI44L and survival of M. tuberculosis H37Rv in the presence of shRNA-IFI44L. (a, b) THP-1 cells transfected with IFI44L-specific shRNA (shRNA-IFI44L) and its scramble shRNA (Scr-shRNA) followed by M. tuberculosis H37Rv infection. (c) Survival of M. tuberculosis H37Rv augmented by CFUs in the presence of shRNA-IFI44L. (d, e) M. tuberculosis H37Rv-infected THP-1 cells with shRNA-IFI44L exhibiting significantly decreased cell apoptosis, as shown in flow cytometry. Values are presented as levels relative to β-actin. ^∗∗P < 0.01; ^∗∗∗P < 0.001.