Table 6.

The results of studied pharmacokinetic parameters of SG-loaded optimized lipospheres and SG reference brand.

Pharmacokinetic variables	Group A SG-OL	Group B SG-brand
T max (h)	10.53 ± 3.56	3.55 ± 2.18
C max (ng/mL)	75.63 ± 3.85	99.66 ± 2.97
MRT0-24 (h)	18.64 ± 3.18	9.5 ± 4.54
AUC0-24 (ng.h/mL)	10275.8 ± 6.53	267.8 ± 9.52
t 1/2 (h)	17.32 ± 1.76	6.08 ± 1.39
K el (h-1)	0.076 ± 1.072	0.359 ± 0.88
AUC0-∞ (ng.h/mL)	14579.7 ± 42.68	738.4 ± 13.76
AUMC0-∞ (ng.h/mL)	238485.6 ± 13.34	55247.7 ± 12.18