Table 5.
Haptoglobin genotype and allele frequency distribution in the study population.
| Groups | SS (n = 102) | AS (n = 55) | AA (n = 60) | p value | |
|---|---|---|---|---|---|
| Hp genotypes | Hp 1-1 | 32 (31.4%)a | 16 (29.1%)a,b | 21 (35%)a,b | ≤0.001∗ |
| Hp 2-1 | 15 (14.7%)b | 23 (41.8%)a | 23 (38.3%)a | ||
| Hp 2-2 | 55 (53.9%)a | 16 (29.1%)b | 16 (26.7%)b | ||
| Hp1S-1S | 25 (24.5%)a,b | 8 (14.5%)a | 9 (15%)a | ≤0.001∗ | |
| Hp1F-1F | 6 (5.9%)a,b,c | 6 (10.9%)a | 9 (15%)a | ||
| Hp1S-1F | 1 (1%)a,b,c | 2 (3.6%)a | 3 (5%)a | ||
| Hp2-1S | 11 (10.8%)a,c | 13 (23.6%)a | 13 (21.7%)a | ||
| Hp2-1F | 4 (3.9%)c | 10 (18.2%)a | 10 (16.7%)a | ||
| Hp2-2 | 55 (53.9%)a,b | 16 (29.1%)a | 16 (26.7%)a | ||
|
| |||||
| Hp allele frequencies | Hp1S | 0.304 | 0.282 | 0.283 | |
| Hp1F | 0.084 | 0.218 | 0.258 | ||
| Hp2 | 0.613 | 0.5 | 0.458 | ||
a, b, and c: values with different letters in the same line are significantly different at p < 0.05; SD: standard deviation; ∗: chi2 test with the Bonferroni adjustment and Fischer test for small size groups.