Table 2.
Independent Predictors of Postdischarge Opioid Use After Cardiac Surgery
| Variable | Pills Taken After Discharge | Pills Taken After Discharge | Univariate P Value | Multivariable P Value |
|---|---|---|---|---|
| Agea | ||||
| <60 y (n = 510) | 5 (0–21) | 14 ± 20 | <.001 | <.001 |
| 60–69 y (n = 487) | 1 (0–14) | 9 ± 15 | ||
| ≥70 y (n = 498) | 0 (0–4) | 4 ± 9 | ||
| Cerebrovascular disease | ||||
| Yes (n = 286) | 0 (0–12) | 9 ± 15 | 0.23 | .013 |
| No (n = 1120) | 1 (0–13) | 9 ± 16 | ||
| Cancer within the past 5 y | ||||
| Yes (n = 91) | 0 (0–10) | 7 ± 13 | .24 | .049 |
| No (n = 1308) | 1 (0–13) | 9 ± 16 | ||
| Primary insurance payorb | ||||
| Medicare (reference) (n = 761) | 0 (0–9) | 7 ± 13 | Reference | |
| Self-pay/no insurance (n = 15) | 0 (0–0) | 2 ± 7 | .08 | .011 |
| Medicaid (n = 113) | 12 (0–37) | 19 ± 21 | <.001 | .50 |
| Military/other governmental (n = 35) | 0 (0–10) | 9 ± 18 | .51 | .89 |
| Commercial (n = 437) | 4 (0–17) | 11 ± 16 | .001 | .48 |
| Health maintenance organization (n = 134) | 3 (0–14) | 10 ± 15 | .09 | .61 |
| Number of pills taken on day before dischargea | ||||
| 0 (n = 710) | 0 | 2 ± 5 | <.001 | <.001 |
| 1–3 (n = 536) | 7 (1–17) | 11 ± 13 | ||
| ≥4 (n = 249) | 24 (10–40) | 28 ± 23 | ||
| Pain during the first week after surgeryb | ||||
| None (n = 80) | 0 | 2 ± 7 | Reference | |
| Minimal (n = 418) | 0 (0–3) | 4 ± 9 | .001 | .001 |
| Moderate (n = 683) | 3 (0–14) | 10 ± 15 | <.001 | <.001 |
| Severe (n = 238) | 14 (2–28) | 19 ± 22 | <.001 | <.001 |
| Length of staya | ||||
| 3–5 d (n = 615) | 3 (0–17) | 11 ± 17 | <.001 | .004 |
| 6–7 d (n = 487) | 1 (0–12) | 9 ± 15 | ||
| ≥8 d (n = 393) | 0 (0–9) | 7 ± 14 | ||
Analyzed as a continuous variable in multivariable regression
Analyzed as a categorical variable in multivariable regression.
Values are median (interquartile range) or mean ± SD. The full model is shown in in Supplemental Table 2.