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. 2021 May 7;83(11):e23254. doi: 10.1002/ajp.23254

Figure 7.

Figure 7

Early stage tau pathology (PKA phosphorylation of tau at pS214Tau) across the aging rhesus monkey cortex shows the same pattern and progression as in human, starting in the ERC layer II cell islands in middle age (a), and then with advanced age in the association cortices such as the dlPFC (b), but not in V1 even in very old animals (c). dlPFC, dorsolateral prefrontal association cortex. Image of tau pathology in A from Paspalas et al. (2018) with permission; images of tau pathology in B and C from Carlyle et al. (2014) with permission