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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: J Pediatr. 2021 Jun 16;238:249–258.e3. doi: 10.1016/j.jpeds.2021.06.009

Table 3:

Sociodemographics and Risk/Benefit Assessment – Research Scenario & Passed Test Questions1

Risk-Benefit Evaluation
Characteristic [N (%)] Risks probably/definitely outweigh benefits Risks and benefits equal Benefits probably/definitely outweigh risks p value
Gender Identity
Male 71 (28.46) 77 (33.07) 97 (38.47) 0.012
Female 94 (36.99) 95 (37.51) 62 (25.50)
Age
18–29 23 (27.85) 30 (39.09) 29 (33.06) 0.615
30–44 47 (36.39) 38 (31.09) 42 (32.51)
45–59 40 (29.43) 53 (39.48) 41 (31.09)
60+ 55 (37.54) 51 (32.32) 47 (30.14)
Race
White 134 (32.21) 147 (36.32) 131 (31.47) 0.845
Black or African American 12 (34.90) 15 (38.54) 11 (26.56)
Asian 7 (33.88) 5 (23.92) 9 (42.20)
Other 12 (40.37) 5 (25.39) 8 (34.24)
Ethnicity
Hispanic 23 (39.08) 13 (27.24) 18 (33.68) 0.388
Non-Hispanic 142 (31.81) 159 (36.80) 141 (31.38)
Income
Less than $49,999 43 (33.48) 48 (41.67) 32 (24.85) 0.206
$50,000 – $99,999 59 (36.23) 53 (31.45) 52 (32.31)
$100,000 or greater 63 (29.94) 71 (34.05) 75 (36.01)
Education
Less than high school 17 (36.37) 11 (29.10) 13 (34.53) 0.718
High school 38 (30.39) 49 (41.64) 35 (27.97)
Some college 42 (32.27) 50 (36.96) 41 (30.78)
Bachelor’s degree or higher 68 (34.16) 62 (31.51) 70 (34.33)
Region
Northeast 33 (34.90) 37 (36.97) 25 (28.12) 0.37
Midwest 29 (27.45) 36 (36.74) 41 (35.81)
South 68 (38.07) 61 (34.90) 48 (27.03)
West 35 (28.35) 38 (33.71) 45 (37.94)
Do you have any children?
No 58 (32.19) 57 (34.78) 61 (33.02) 0.872
Yes 107 (33.48) 115 (35.90) 97 (30.62)
Have any of your children ever had a serious illness?
No 90 (34.33) 100 (37.80) 72 (27.88) 0.0744
Yes 17 (29.42) 15 (26.84) 25 (43.75)
Have you ever enrolled in medical research yourself?
No 151 (33.22) 155 (35.22) 145 (31.56) 0.877
Yes 14 (29.30) 17 (37.16) 14 (33.54)
Have you ever enrolled any of your children in medical research?
No 105 (34.25) 109 (35.82) 91 (29.93) 0.396
Yes 2 (17.75) 6 (37.57) 6 (44.68)
Attitudes Toward Research
Medical researchers can be trusted to protect the people who take part in their studies.
Disagreed 38 (46.28) 26 (35.39) 14 (18.33) <0.0001
Neutral 76 (36.34) 85 (40.63) 47 (23.03)
Agreed 46 (23.21) 60 (30.95) 94 (45.84)
People have some responsibility to help others by participating in research.
Disagreed 57 (53.02) 36 (32.25) 16 (14.72) <0.0001
Neutral 55 (31.45) 78 (46.10) 41 (22.45)
Agreed 48 (22.01) 57 (28.76) 98 (49.23)
Medical research is important for helping to improve health and combating disease
Disagreed 2 (35.70) 0 (0) 3 (64.30) N/A
Neutral 13 (44.72) 15 (54.27) 1 (1.01)
Agreed 145 (31.85) 156 (34.92) 151 (33.22)
1

Counts unweighted, proportions weighted, p values based on weighted analysis