Table 2:
Baseline Characteristics of Subjects
| Derivation AP Cohort (n=46) | Derivation Controls (n=20) | Validation AP Cohort (n=25) | Validation Controls (n=10) | P-value | |
|---|---|---|---|---|---|
| Age (years) | 13.7 (9.1-16.2) | 12.8 (5.9-16.4) | 14.2 (11.1-17.3) | 10.4 (6.3-15.9) | 0.45 |
| Sex (male) | 24 (52%) | 11 (55%) | 13 (52%) | 6 (60%) | 0.98 |
| BMI percentile | 73.2 (38.5-97.0) n=39 | 48.6 (40.3-77.3) n=18 | 66.9 (31.8-96.6) | 64.3 (41.4-66.5) n=8 | 0.60 |
| Etiology | NA | NA | |||
| 1. Divisum/obstructive | 1 (2%) | 2 (8%) | 0.28 | ||
| 2. Biliary/gallstone | 6 (13%) | 7 (28%) | 0.20 | ||
| 3. Trauma | 2 (4%) | 0 (0%) | 0.54 | ||
| 4. Genetic† | 8 (17%) | 1 (4%) | NA | ||
| 5. Infectious/systemic disease/metabolic | 12 (26%) | 2 (8%) | 0.12 | ||
| 6. Idiopathic/other | 10 (22%) | 8 (32%) | 0.34 | ||
| 7. Drug | 6 (13%) | 5 (20%) | 0.50 | ||
| 8. Post ERCP | 1 (2%) | 0 (0%) | 1.00 | ||
| Index case | 37 (80%) | 21 (84%) | 1.00 | ||
| SAP * | 10 (22%) | 6 (24%) | 0.83 |
Median (25th-75th percentile) or n (%). NA = Not applicable
*
SAP = Combined moderately severe and severe AP;
†
Not all patients received genetic testing