Figure 6. Pcolce2 mRNA abundance correlates with adipose mass in both mice and humans.
(A-D) Correlations between mouse Pcolce2 mRNA abundance with visceral adipose tissue or subcutaneous adipose tissue. Data were obtained from the study of 100 inbred strains of female or male mice from the Hybrid Mouse Diversity Panel. Experimental details are described in Methods. (E-G) Correlations between human subcutaneous fat Pcolce2 mRNA abundance expressed as counts per million reads (cpm) with (E) body mass index (BMI), (F) percent fat mass and (G) plasma insulin are shown. All samples were obtained from obese patients undergoing bariatric surgery with metabolic information contained in Supplemental Table II and experimental details described in Methods.