Table 3.

Odds ratios (95% CI) for Polygenic Risk Score and Asthma in GERA^*

	Non-Hispanic Whites (N=51,478)	Asians (N=5,152)	Hispanics (N=4,405)	African Americans (N=2,070)
Standard PRS	1.16 (1.14 to 1.18)	1.10 (1.04 to 1.17)	1.12 (1.05 to 1.19)	1.05 (0.97 to 1.15)
Lasso Sum PRS (Primary Analysis)	1.20 (1.18 to 1.23)	1.18 (1.10 to 1.27)	1.17 (1.10 to 1.26)	1.10 (0.99 to 1.22)
Lasso Sum PRS (Secondary Analysis)	1.28 (1.25 to 1.31)	---	--	--

^*Odds ratios are for a standard deviation increase in PRS within a given population. All models have been adjusted for age, sex and BMI