Table 6.

Principal Components of Cortical Thickness Clusters Predicting Treatment Response

Parameter	Mean	SE	95% CI	z	p
(Intercept)	6.8	9.6	−9.7 – 30.6	0.7	0.477
PC 4	6.6	9.1	−6.4 – 29.3	0.7	0.47
PC 5	6.7	7.5	−3.9 – 23.8	0.9	0.37
PC 7	6.1	9.4	−7.5 – 31.1	0.6	0.517
PC 10	15.1	8.7	2.1 – 34.5	1.7	0.084
PC 12	17.2	9.8	3.8 – 41.0	1.7	0.081
PC 14	16.8	10.0	1.1 – 41.1	1.7	0.094
PC 15	1.5	8.1	−14.5 – 20.6	0.2	0.852
PC 20	12.0	7.1	1.2 – 28.9	1.7	0.091
PC 25	16.5	8.7	2.4 – 33.8	1.9	0.059
PC 27	−10.9	8.3	−29.3 – 3.3	−1.3	0.191
PC 28	1.5	6.3	−10.4 – 14.4	0.2	0.809
PC 29	11.6	11.6	−4.7 – 37.8	1.0	0.314
PC 30	17.8	9.2	4.7 – 38.1	1.9	0.052
Time × PC 4	21.6	12.9	0.0 – 53.6	1.7	0.095
Time × PC 7	−14.2	11.7	−38.6 – 6.8	−1.2	0.225
Time × PC 10	−15.2	11.9	−44.7 – 2.2	−1.3	0.204
Time × PC 14	−21.8	12.2	−50.4 – −0.1	−1.8	0.073
Time × PC 15	−26.0	13.7	−56.7 – −5.8	−1.9	0.057
Time × PC 25	−12.1	10.3	−37.8 – 4.3	−1.2	0.24
Time × PC 28	21.3	11.2	2.4 – 43.0	1.9	0.057
Time × PC 29	−14.5	12.0	−41.9 – 4.2	−1.2	0.224
Time	1.3	1.5	−1.1 – 4.7	0.8	0.396
Age	−0.2	0.1	−0.5 – 0.0	−1.6	0.119
Sex (Male)	3.0	2.2	0.0 – 7.7	1.3	0.181
Baseline HDRS	0.3	0.2	−0.1 – 0.8	1.6	0.112

Abbreviations: PC=principal component, SE=standard error, CI=confidence interval; HDRS= Hamilton Depression Rating Scale