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. 2021 Oct 6;24(11):103223. doi: 10.1016/j.isci.2021.103223

Figure 5.

Figure 5

STK39 knockdown suppressed CCA cell proliferation and metastasis in vivo

(A) Nude mice were subcutaneously injected with STK39 stable knockdown or overexpression cells. The tumor volume and average weight were determined.

(B) IHC analysis of STK39 and Ki-67 in the tumors derived from mice, scale bar, 50μm.

(C) STK39 stable knockdown or overexpression cells were injected into the tail vein of nude mice to induce lung metastasis, and representative bioluminescent images were captured; liver metastatic nodules were subjected to HE staining as indicated, scale bar, 200μm. ∗p<0.05; ∗∗p<0.01; ∗∗∗p<0.001. Data were shown as mean ± SEM.