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. 2021 Oct 23;413(27):6747–6767. doi: 10.1007/s00216-021-03665-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — In vivo dopamine and serotonin monitoring using rapid pulse voltammetry with partial least squares regression (RPV-PLSR) analysis. a, b Time courses of dopamine or serotonin at various dorsoventral striatal positions measured with RPV-PLSR (n = 3 at 2.80 mm, n = 5 at 2.95 mm, n = 7 at 3.15 mm, and n = 3 at 3.35 mm for a total of 18 recordings in a single representative mouse). c, d Time courses of dopamine or serotonin measured in dorsal striatum (dSTR) in response to representative sequential 40 Hz and 30 Hz optical stimulations of midbrain dopamine neurons (n = 1)