Table 2.

Microbial virulence factor abundance in TT. Virulence factors found to be in higher abundance in TT when compared with contralateral NT samples. Predicted function, associated microbial taxa, and significance values are summarized below

Significantly abundant virulence factors in tumor tissue
Taxa match	Gene annotation	Individual p value
Streptococcus pneumoniae Hungary 19A-6	Choline binding protein CVF122	0.0291
Treponema denticola ATCC35405	Major outer sheath protein (Fibronectin binding protein AI239)	< 0.0001
Mycoplasma penetrans HF-2	p35 lipoprotein homolog	0.0005
Acinetobacter baumannii AB0057	AB57 0984. transcriptional regulator, LysR (Heme utilization)	< 0.0001
Shigella dysenteriae Sd197	ospC4 Mxi-Spa TTSS effector controlled by VirB CVF494	0.0169
Bacillus cereus ATCC 10987	O-antigen polymerase (wzy) Polysaccharide capsule CVF567	0.0013
Haemophilus somnus 2336	lic2A glycosyl transferase family 25 LOS CVF494	0.0004
Streptococcus gordonii str. Challis	csh B surface-associated protein Csh B Fibronectin binding protein AI195	0.0199
Streptococcus gordonii str. Challis	csh A surface-associated protein Csh B Fibronectin binding protein AI194	0.0050