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. 2021 Oct 27;12:6201. doi: 10.1038/s41467-021-26431-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Percentage of immune cells detected in the peripheral blood (a, c, e, g, i) and spleen (b, d, f, h, j). a, b Foxp3⁺CD4⁺ T regulatory cells; c, d Foxp3⁺CD8⁺ T regulatory cells; e, f CD11b⁺Gr1⁺ cells (MDSCs); g, h effector CD4⁺ cells; i, j effector CD8⁺ cells. k Percentage of GrB⁺CD8⁺ cells and l GrB⁺CD4⁺ cells in the spleen. The data is represented as scatter plots showing mean values ± SEM. One-way ANOVA with Tukey post hoc analysis was used to determine statistical significance with *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 compared to AL.a AL, n = 10; FMD, n = 9; LCC, n = 10; CR, n = 10. b, c, e, g-l AL, n = 10; FMD, n = 10; LCC, n = 10; CR, n = 10. d AL, n = 9; FMD, n = 10; LCC, n = 10; CR, n = 8. f AL, n = 9; FMD, n = 10; LCC, n = 10; CR, n = 9 mice per treatment group. Source data are provided as a Source Data file.