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. 2021 Oct 27;11:21206. doi: 10.1038/s41598-021-00483-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Prediction of the binding sites of transcription factors and the network of TFs and downstream targets. (A) Predicted TFs (MYC and ARNT) in ACPs. (B) Predicted TFs (ELK1 and ERR1) in PCPs. The color of the outer node indicates the differential expression levels revealed through label-free quantification, and the color of the inner node indicates the differential expression level revealed through TMT quantification.