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. 2021 Oct 27;12(11):1009. doi: 10.1038/s41419-021-04284-5

Fig. 2. Lipid peroxidation in keratinocytes of psoriasis lesions is characterized at a single-cell level.

Fig. 2

A UMAP clustering of 12,025 cells by differentially expressed markers. B Gene expression patterns of marker genes for the cell subtypes. C The correlation between Th22Th17 pathway activity and lipid oxidation pathway activity in keratinocytes, fibroblasts, macrophage/dendritic cells, endothelial cells, melanocytes, and pericytes. D UMAP clustering of keratinocytes of normal and psoriatic samples. E Distributions of lipid oxidation pathway activity in different keratinocyte subtypes. **P < 0.01, ***P < 0.001. UMAP uniform manifold approximation and projection.