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. 2021 Oct 27;11:21221. doi: 10.1038/s41598-021-98949-y

Table 1.

Cytotoxicity of flavonoids against Vero cells.

Compound CC50 ± SEM (µg/mL) MNTD80 ± SEM (µg/mL)
Silymarin 749.70 ± 3.41 202.30 ± 3.68
Baicalein 271.03 ± 6.57 122.95 ± 2.37
Baicalin 54.64 ± 0.76 19.15 ± 0.07

Different concentrations of silymarin, baicalein, and baicalin were tested for cytotoxicity in Vero cells by MTS assay. CC50 refers to the half maximum cytotoxic concentration, whereas MNTD80 is the dose at which 80% of the cells are viable. Data were acquired from three independent experiments and presented as mean ± standard error mean (SEM).