Skip to main content
. 2021 Oct 27;12(11):1005. doi: 10.1038/s41419-021-04285-4

Fig. 2. CD8+ T cells, CD4+ T cells, and Tregs have distinctive sensitivity patterns to short-term in vivo treatment with venetoclax.

Fig. 2

FOXP3-IRES-GFP mice were treated daily for 7 days with 25, 50, or 100 mg/kg venetoclax or vehicle control. A Representative flow plots of CD8+ T cells, CD4+ T cells and Tregs from the spleens of mice treated with 100 mg/kg venetoclax compared to vehicle. B Percentage and C Absolute number of CD8+ T cells, CD4+ T cells, and Tregs isolated from the spleens of treated animals. n ≥ 5 for each group of three independent experiments. Data represented as means ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.