Fig. 6. Long-term in vivo treatment with venetoclax following bone marrow transplantation results in similar increases in BCL-2 levels but different cell death sensitivity between T cell subtypes.

A Protein levels of naïve CD8⁺ T cells, CD4⁺ T cells and Tregs one-month post-transplant. n ≥ 3 mice/group. B CD8⁺ T cells, CD4⁺ T cells, and Tregs from mice at the 2 month timepoint were treated with apoptotic stimuli for 24 h. Viability of T cells was assessed by Annexin V/PI staining with Annexin V^negPI^neg cells considered viable. n ≥ 4 mice/group. Data represented as means ± SEM of two independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.