Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Oct 14;12:712317. doi: 10.3389/fphys.2021.712317

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Hambali, Kumar, Hashim, Maniam, Mehat, Cheema, Mustapha, Adenan, Stanslas and Hamid.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The possible targets of Centella asiatica as neuroprotection in hypoxia-induced neuroinflammation – the pathophysiology of AD. We propose several targets for Centella asiatica (CA) which (1) suppresses the formation of Aβ plaques (2) inhibits or suppresses the dysregulation of calcium homeostasis (3) attenuates the effect of Aβ plaques formation towards the dysregulation of calcium homeostasis, oxidative stress and neuroinflammation and (4) attenuates the activation of NF-κβ signalling pathway as well as enhances the activation of Nrf2 signalling pathway, resulting in neuroprotection.